Formulation and Evaluation Pharmaceutical aqueous gel of powdered Guava Leaves for Mouth Ulcer Treatment

  • Sabir Shaikh S. Kant Health care R&D Centre
  • Amol Shete Krishna institute of Pharmacy of Krishna institute medical sciences Deemed university
  • Rajendra Doijad Shree Santkrupa College of Pharmacy Ghogaon
Keywords: Guava Leaves Powder, Gel, Mouth Ulcer

Abstract

The objectives of present investigation were to formulate and evaluate herbal gel for mouth ulcer treatment of dried powdered guava leaves.
Herbal gel was prepared by using different concentration of powdered guava leaves and Carbopol 934, Propylene glycol as a gel base. Formulations were evaluated for various parameters
Infrared spectroscopy revealed that there was no interaction between powdered Guava leaves and Polymer. The formulated gel was transparent, homogeneous and pH ranges from 7 to 7.5. Formulation showed acceptable rheological behaviour with applicable Spreadability and Extrudability properties. Anti-fungal studies of formulations showed excellent efficacy against Aspargilious aureus, Candida albicans.
From the experimental evidence of invitro studies it was observed that powdered guava leaves contain flavonoids so it showed significant antioxidant effect.
Developed herbal formulation was stable, safe and effective over to synthetic formulations for the treatment of mouth ulcer.

Author Biographies

Sabir Shaikh, S. Kant Health care R&D Centre

S. Kant Health care R&D Centre
Turbhe, Navi Mumbai, Maharashtra, India

Amol Shete, Krishna institute of Pharmacy of Krishna institute medical sciences Deemed university

Department of pharmaceutics,
Krishna institute of Pharmacy of Krishna institute medical sciences Deemed university,
Karad, Maharashtra, India.

Rajendra Doijad, Shree Santkrupa College of Pharmacy Ghogaon

Department of Pharmaceutics and Quality Assurance,
Shree Santkrupa College of Pharmacy Ghogaon, Karad,
Maharashtra, India.

Published
2018-04-01
How to Cite
[1]
Shaikh, S., Shete, A. and Doijad, R. 2018. Formulation and Evaluation Pharmaceutical aqueous gel of powdered Guava Leaves for Mouth Ulcer Treatment. PharmaTutor. 6, 4 (Apr. 2018), 32-38. DOI:https://doi.org/10.29161/PT.v6.i4.2018.32.
Section
Articles